[rmike]

A recent study suggested that mikeh from Norf Derkota has 1,000 times the amount of brain cells as any other human being. True story guys, I heard it somewhere. lol jk

[aild54]

****, I forgot to post this morning's workout.

5 minutes on the treadmill
Dynamic stretches
Flat BB bench
45x13 75x8 (warm-ups)
95x6 1
115x6
135x5
140x4
BB rows
45x13 65x8 (warm-ups)
95x6
105x6
115x6
125x5
Push press -ss-RG pulldowns
65x6-ss-60x6
85x5-ss-70x6
90x4-ss-90x6

Anddd now it's time for bed.

[projecthatch92]

bed? i just got home from class :(

[Thomas_Rivera]

Originally Posted by mikeh40+

benadryl is good for cleaning the receptors yes, but the down side is it makes you sleeeeepy!! i do use it at night off and on, but here again you can build up a tolerance as well, for me i have a high tolerance for almost everything, must be i have like a ton of extra brain cells or something,

This, i've never heard. IT has my interests.

[rmike]

Ive heard of people using it for that during cycles of clen or albuterol. I know its a anticholinergic and a histamine antagonist and I always wondered where the connection was with stimulants other than the fact that it makes you tired but I have heard many people use it. It must have some other antagonistic properties as well. It is an interesting topic

[aild54]

Originally Posted by Thomas_Rivera

This, i've never heard. IT has my interests.

Thomassss, while you're here, I thought of another question. Artificial sweeteners. I've heard to stay away from Splenda, and when I looked at the box, it has malto in it, but no calories. Should I avoid all artifical sweeteners, or just use them sparingly?

Anddd does anybody have any studies or anything for the receptor clearing thing?

[aild54]

This morning's workout....
5 minutes on the treadmill
Dynamic stretches
SLDL
45x13 75x8 (warm-ups)
135x6
165x6
195x6
215x5
Squats
95x6
125x6
155x6
165x5

[Thomas_Rivera]

Originally Posted by aild54

Thomassss, while you're here, I thought of another question. Artificial sweeteners. I've heard to stay away from Splenda, and when I looked at the box, it has malto in it, but no calories. Should I avoid all artifical sweeteners, or just use them sparingly?

Anddd does anybody have any studies or anything for the receptor clearing thing?

Some people are sensitive to them some aren't. Usually I've found that I'm more sensitive to them during the initial month, test around and see how you feel.

[aild54]

Originally Posted by Thomas_Rivera

Some people are sensitive to them some aren't. Usually I've found that I'm more sensitive to them during the initial month, test around and see how you feel.

Okay, so I can test it out like a month or two into it?

[Thomas_Rivera]

A month into it is fine.

[aild54]

Sweet, thanks, man.

[Teran]

Originally Posted by mikeh40+

but your correct in the statement, the older one gets, damn it there is that word again.. the more ones tolerance level becomes, i believe the tolerance issue has something to do with amount of receptors you have? i`m not sure on that so dont quote me, or its something in the brain that one is more sensitive to stimulants, oh hell the more i type the more i see that i have no fricking idea either, i`ll just end now.

Usually as one ages, the dosages of medications need to be reduced as they have a stronger than desired affect on the individual. Not all people are created, or age, equally though. So tolerance and aging is almost always associated with a decreased tolerance to certain medications as one ages.

However (big however here), there are certain drugs that will always have tolerance thresholds that people reach regardless of age. The most clear example is an elderly cancer patient who is taking certain types of pain medications. Those medications are problematic in that people build up a tolerance to them and need more to have the same effect. They end up taking dosage levels near the end of their time that would easily kill a person off the street 3 times over, if that person off the street took that increased dosage initially.

Hope that helps with the tolerance discussion.

My opinion...don't mess with Benadryl if ya can avoid it. It really isn't good for you in general, except as an anti-histamine. It has a couple of different medical uses but there is a lot more harm than good that can come from using it unfortunately. Unless of course it's directly needed for a specific medical issue.

As far as it affecting receptors, I don't know, never heard about a study relating to that, so can't elaborate. Even if it did, I'd prolly avoid it, unless it was absolutely needed.

The *cough, geezer, cough* poster, damm that coughs back...that brought up the receptor topic, it's one that they are looking into with Alzheimers. Trying to clean em up. They have had some trials but nothing promising yet. If Benadryl cleaned em, I think they wouldn't be spending a ton of money on trying to find something that did. It might affect them in another way, and if it does, I haven't read up on it enough to tell ya how.

[Thomas_Rivera]

I've read things about Reset AD to resensitize the body. Not sure though.

[aild54]

Solid info, Teran. If you don't mind me asking, how do you know all of this? You seem really educated on the matter.

[mikeh40+]

Originally Posted by Teran

Usually as one ages, the dosages of medications need to be reduced as they have a stronger than desired affect on the individual. Not all people are created, or age, equally though. So tolerance and aging is almost always associated with a decreased tolerance to certain medications as one ages.

However (big however here), there are certain drugs that will always have tolerance thresholds that people reach regardless of age. The most clear example is an elderly cancer patient who is taking certain types of pain medications. Those medications are problematic in that people build up a tolerance to them and need more to have the same effect. They end up taking dosage levels near the end of their time that would easily kill a person off the street 3 times over, if that person off the street took that increased dosage initially.

Hope that helps with the tolerance discussion.

My opinion...don't mess with Benadryl if ya can avoid it. It really isn't good for you in general, except as an anti-histamine. It has a couple of different medical uses but there is a lot more harm than good that can come from using it unfortunately. Unless of course it's directly needed for a specific medical issue.

As far as it affecting receptors, I don't know, never heard about a study relating to that, so can't elaborate. Even if it did, I'd prolly avoid it, unless it was absolutely needed.

The *cough, geezer, cough* poster, damm that coughs back...that brought up the receptor topic, it's one that they are looking into with Alzheimers. Trying to clean em up. They have had some trials but nothing promising yet. If Benadryl cleaned em, I think they wouldn't be spending a ton of money on trying to find something that did. It might affect them in another way, and if it does, I haven't read up on it enough to tell ya how.

so tolerance becomes diminished as you get older your saying, well i`ll have to read up on that a bit, from my views and personal use i have found the opposite to be the case, there are many medications that i have had to adjust to a higher dosage after i`ve been on them for a long period they dont seem to work as well as the lower dosage did, but the pain meds for sure i agree on, those damn things seem designed to make you want more and more,
the benadryl receptors i belive allstar had posted about cleaning receptors, so i`m not 100% on just what receptors they are supposed to clean, thats one i`ll have to read up on as well,, unless you beat me to it,, but you did bring up a good point about Benadryl and other medications, like for example my wife has real chronic migranes, anyways the last visit to the E.R. they gave her a ****tail of I.V. drugs and one of the vials was Benadryl, the anit-histamine did something to help the other drug do its thing, so it does have some other benefits

[aild54]

That's actually pretty cool they did that at a hospital, Mike. I'm sorry to hear about your wife, though.

This morning, I knew it was going to take me a little longer, so I hit the weights 15 minutes early. Good stuff.

5 minutes on the treadmill
Dynamic stretches
Lat Pulldowns
35x13x2 50x8 (warm-ups)
70x6
80x6
90x5
85x5
DB Rows
30'sx6
40'sx6
50'sx6
55'sx6 Personal best... I think

BB Shrugs
155x6
185x6
205x6

BB curls
45x10
55x6
45x21's

[mikeh40+]

saweeet a PB!! nice job chris, and those 21`s on the BB curls must have been killer !!

[Teran]

Originally Posted by aild54

Solid info, Teran. If you don't mind me asking, how do you know all of this? You seem really educated on the matter.

Have worked in the medical field for a while. Know some things, from personal and family experience and some from work, and the people I have access to at work. No I'm not an MD.

Originally Posted by mikeh40+

so tolerance becomes diminished as you get older your saying, well i`ll have to read up on that a bit, from my views and personal use i have found the opposite to be the case, there are many medications that i have had to adjust to a higher dosage after i`ve been on them for a long period they dont seem to work as well as the lower dosage did, but the pain meds for sure i agree on, those damn things seem designed to make you want more and more,

A "normal" dose for someone in their 20's or 30's of a given medication (read typical medication), is usually too high of a dose of the same medication for someone in their 60's or 70's. We will lower the "normal" dose a bit for someone who is older so we get the desired result and don't overdose them. If you have been on something for a while and needed a bigger dose to get the same results, then yes, you built up a tolerance to that medication and have a threshold to reach before it becomes effective. Which is different than requiring less of a medication (being more susceptible or less tolerant are prolly better word choices) to have the same results because of your increased age (increased age being 50-60+).

Originally Posted by mikeh40+

the benadryl receptors i belive allstar had posted about cleaning receptors, so i`m not 100% on just what receptors they are supposed to clean, thats one i`ll have to read up on as well,, unless you beat me to it,

I'll try and find something about it, but I don't like the off label uses for Benadryl in general, so you'll probably beat me to it.

Originally Posted by mikeh40+

but you did bring up a good point about Benadryl and other medications, like for example my wife has real chronic migranes, anyways the last visit to the E.R. they gave her a ****tail of I.V. drugs and one of the vials was Benadryl, the anit-histamine did something to help the other drug do its thing, so it does have some other benefits

"It has a couple of different medical uses..."

One of Benadryl's medical uses especially in the ER setting is as an anti-emetic. If they gave her pain medication of some kind, morphine, dilaudid etc. they will almost always give an anti-emetic with it (reglan, compazine) to keep em from yakin all over the place. Benadryl also has a sedative affect (like you said sssslllllleeeeeeepppppyyyyy) on most people, so they can keep someone who has a migraine, from pukin, from movin around much, and potentially get them to rest, all of which helps to treat the migraine (along with the pain medication). Some people, usually kids, can have the opposite reaction to Benadryl, they get allll kinds of crazy and wired from it, and it can negatively affect some people's cardiac ability. Hence why I usually suggest to people (like any medication) to only use it if ya need to, as side effects can be a real bitch.

[mikeh40+]

Originally Posted by Teran

Have worked in the medical field for a while. Know some things, from personal and family experience and some from work, and the people I have access to at work. No I'm not an MD.



A "normal" dose for someone in their 20's or 30's of a given medication (read typical medication), is usually too high of a dose of the same medication for someone in their 60's or 70's. We will lower the "normal" dose a bit for someone who is older so we get the desired result and don't overdose them. If you have been on something for a while and needed a bigger dose to get the same results, then yes, you built up a tolerance to that medication and have a threshold to reach before it becomes effective. Which is different than requiring less of a medication (being more susceptible or less tolerant are prolly better word choices) to have the same results because of your increased age (increased age being 50-60+).



I'll try and find something about it, but I don't like the off label uses for Benadryl in general, so you'll probably beat me to it.



"It has a couple of different medical uses..."

One of Benadryl's medical uses especially in the ER setting is as an anti-emetic. If they gave her pain medication of some kind, morphine, dilaudid etc. they will almost always give an anti-emetic with it (reglan, compazine) to keep em from yakin all over the place. Benadryl also has a sedative affect (like you said sssslllllleeeeeeepppppyyyyy) on most people, so they can keep someone who has a migraine, from pukin, from movin around much, and potentially get them to rest, all of which helps to treat the migraine (along with the pain medication). Some people, usually kids, can have the opposite reaction to Benadryl, they get allll kinds of crazy and wired from it, and it can negatively affect some people's cardiac ability. Hence why I usually suggest to people (like any medication) to only use it if ya need to, as side effects can be a real bitch.

very well explained, i would rep you again if i could bro, you came across in a positive and helpful manor which makes learning different things so much more enjoyable, the fact you didnt talk down or show case is a tribute to who you are.

[projecthatch92]

I'll rep him for ya mikey

[mikeh40+]

Originally Posted by projecthatch92

I'll rep him for ya mikey

thanks bro!!

[aild54]

Teran, do you feel that most meds are overrated and unnecessary for the majority of people? For example, do you think too many doctors give out antibiotics and things of that nature when most people just need rest to get better?

And thanks, Mike. When I do lighter weight at the end of my workouts and stuff, I alwaysss go slower with pauses at the peak of the ROM. It gives me a sick nasty pump. There's not really a purpose aside from that, but that, along with pauses for every rep for my back workouts, has brought up my left lat considerably.

[rmike]

Originally Posted by Teran

Usually as one ages, the dosages of medications need to be reduced as they have a stronger than desired affect on the individual. Not all people are created, or age, equally though. So tolerance and aging is almost always associated with a decreased tolerance to certain medications as one ages.

However (big however here), there are certain drugs that will always have tolerance thresholds that people reach regardless of age. The most clear example is an elderly cancer patient who is taking certain types of pain medications. Those medications are problematic in that people build up a tolerance to them and need more to have the same effect. They end up taking dosage levels near the end of their time that would easily kill a person off the street 3 times over, if that person off the street took that increased dosage initially.

Hope that helps with the tolerance discussion.

My opinion...don't mess with Benadryl if ya can avoid it. It really isn't good for you in general, except as an anti-histamine. It has a couple of different medical uses but there is a lot more harm than good that can come from using it unfortunately. Unless of course it's directly needed for a specific medical issue.

As far as it affecting receptors, I don't know, never heard about a study relating to that, so can't elaborate. Even if it did, I'd prolly avoid it, unless it was absolutely needed.

The *cough, geezer, cough* poster, damm that coughs back...that brought up the receptor topic, it's one that they are looking into with Alzheimers. Trying to clean em up. They have had some trials but nothing promising yet. If Benadryl cleaned em, I think they wouldn't be spending a ton of money on trying to find something that did. It might affect them in another way, and if it does, I haven't read up on it enough to tell ya how.

Very good explanation. Id rep ya again if I could

Originally Posted by aild54

That's actually pretty cool they did that at a hospital, Mike. I'm sorry to hear about your wife, though.

This morning, I knew it was going to take me a little longer, so I hit the weights 15 minutes early. Good stuff.

5 minutes on the treadmill
Dynamic stretches
Lat Pulldowns
35x13x2 50x8 (warm-ups)
70x6
80x6
90x5
85x5
DB Rows
30'sx6
40'sx6
50'sx6
55'sx6 Personal best... I think

BB Shrugs
155x6
185x6
205x6

BB curls
45x10
55x6
45x21's

Originally Posted by mikeh40+

very well explained, i would rep you again if i could bro, you came across in a positive and helpful manor which makes learning different things so much more enjoyable, the fact you didnt talk down or show case is a tribute to who you are.

Great work buddy! Them pb's make us feel the best! Keep it up, i like what your doing brotha

Originally Posted by aild54

Teran, do you feel that most meds are overrated and unnecessary for the majority of people? For example, do you think too many doctors give out antibiotics and things of that nature when most people just need rest to get better?

And thanks, Mike. When I do lighter weight at the end of my workouts and stuff, I alwaysss go slower with pauses at the peak of the ROM. It gives me a sick nasty pump. There's not really a purpose aside from that, but that, along with pauses for every rep for my back workouts, has brought up my left lat considerably.

I can say from a vetirinary medical standpoint that doc's do overprescribe alot of antibiotics. Its to the point now where I cant even use cephalosporins in the kennel that I manage because they are innefective. I rely on tetracyclines alot because they are cost effective but its very clear to me that we build tolerances and render some drugs useless over time. However, in 2 or 3 years some of the drugs that I cant use now will become effective once again. Its a cycle that we created within our kennel and its strange because, inspite of my best efforts, what I have in there stays in there and other kennels will be able to successfully use the same drugs that I cant. Its so interesting to me to follow the etiology of some of these microorginisms in vet medicine. Its the virus's that scare the crap out of me, like parvo and distemper.
Wow sorry for the retarted long post buddy!lol
I think that psych meds are waaay to over prescribed, especially in children. We never had alot of the stuff that they diagnose today. Sometimes I think pharmaceutical companies invent these conditions. Thats just my opinion though. My son was diagnosed with autism and I question it everyday

[Teran]

Originally Posted by aild54

Teran, do you feel that most meds are overrated and unnecessary for the majority of people? For example, do you think too many doctors give out antibiotics and things of that nature when most people just need rest to get better?

Yes. Antibiotics are WAY overprescribed. Most people with a cold or flu are still of the mindset for whatever reason, that they need antibiotics to cure it, no matter how many times ya tell them it's a virus that they have, and antibiotics won't affect it at all because antibiotics are for bacteria (infections).

A lot of MD's now have gone away from diagnostic testing (read lazy MD's) and just prescribe medications, as it is easier to write a prescription than it is to diagnose, and a lot of people want a "pill" regardless of what the problem is, since we as a society have conditioned people to believe that a medicine will make everything better.

Originally Posted by rmike

I can say from a vetirinary medical standpoint that doc's do overprescribe alot of antibiotics. Its to the point now where I cant even use cephalosporins in the kennel that I manage because they are innefective. I rely on tetracyclines alot because they are cost effective but its very clear to me that we build tolerances and render some drugs useless over time. However, in 2 or 3 years some of the drugs that I cant use now will become effective once again. Its a cycle that we created within our kennel and its strange because, inspite of my best efforts, what I have in there stays in there and other kennels will be able to successfully use the same drugs that I cant. Its so interesting to me to follow the etiology of some of these microorginisms in vet medicine. Its the virus's that scare the crap out of me, like parvo and distemper.
Wow sorry for the retarted long post buddy!lol
I think that psych meds are waaay to over prescribed, especially in children. We never had alot of the stuff that they diagnose today. Sometimes I think pharmaceutical companies invent these conditions. Thats just my opinion though. My son was diagnosed with autism and I question it everyday

Agree with a lot of what ya said. I think there are a lot of "conditions" that are real and need medical assistance to provide the person with a decent quality of life. I also think there are a lot of "created" conditions that aren't really medical/psych conditions at all, just a way for medical people to make easy $$ off of by "treating" them.

[mikeh40+]

ok so the receptor cleaning thing is this,

Benadryl
By Anthony Roberts

As you know, Benadryl, at around 50-100mgs/night before bed (every 3rd week or so, for that week) will help with keeping your beta-receptors working properly. Beta receptors are embedded in the cell's outer phospholipid membrane. The stability of the membrane has a lot to do with the proper function of the receptors.

Methylation of the phospholipids is stimulated by the binding of beta agonists to their receptors. Methylated phospholipids are foreign to the body, and when the body recognizes tham as foreign, it breaks them down with phospholipase A2. This changes the structure of the outer membrane which results in desensitizaton of the beta receptors. On the other hand, agents that inhibit phospholipase A2 slow desensitization.

Cationic ampiphylic drugs are known for their ability to inhibit phospholipase A2. Benadryl (diphenhydramine) is a cationic ampiphylic drug.

Ergo, Benadryl slows desensitization of Beta receptors (i.e. Upgrades them) by inhibiting phospholipase A2, which is the enzyme that breaks down methylated phospholipids, and this action in turn keeps the phospholipid membrane stable, and thus keeps the receptors functioning properly.

This will allow you to use clen for much longer and it'll still have the same effects. Also, since Benadryl is an anti-histamine, and histamines have a direct effect on beta-adrenoreceptors (not just Beta-2?s but all of them), using an anti-histamine will have a direct effect on reducing beta-receptor stimulation, and thus upregulating your beta-receptors.

In addition, many athletes have issues sleeping while on clen, and Benadryl before bed can help with that.

Finally, stimulants are well known to cause Anxiety in some, and clenbuterol is a stimulant; Benadryl is widely prescribed as an OTC anti-anxiety medication, when people go to emergency rooms with classic panic attack/anxiety symptoms.

SO using benadryl with your clen will upgrade your receptors, help you sleep, and avert stimulant based anxiety.

this is about the brunt of all i found for how benadryl works and for what receptors is "cleans" if you want to call it that,

[Teran]

Originally Posted by mikeh40+

ok so the receptor cleaning thing is this, this is about the brunt of all i found for how benadryl works and for what receptors is "cleans" if you want to call it that,

I looked online for a short time for stuff, doesn't seem like anything with any backing was posted anywhere. The article you quoted seems to be a theory piece, so if I can find more info I'll pass it on. My 2 cents at this point is that I'm not convinced.

[aild54]

Good stuff on here, guys. Thank you all.

But, Mike, couldn't you just use lower dosages of certain meds? I mean, so the dogs don't build a tolerance to much of anything, or it would at least take longer?
Teran, I totally agree. Do you feel that hand sanitizer is unnecessary for the general population? I ask that, because my school got them, and everybody uses them like every hour (stupid, I know). Everybody else around me is sick... except me. I even kissed a girl, and the next day she was diagnosed with swine flu. Am I just some freak of nature?

[projecthatch92]

look at you chris, up bright and early on a saturday eh?

[HawaiianPride.]

[QUOTE=projecthatch92;719677]look at you chris, up bright and early on a saturday eh?[/QUOT]

Only dedicated guys like us will sacrifice a good friday night to eat, sleep, rest, then train balls to the wall Saturday morning lol.

[projecthatch92]

I've been up since 6 :(