[russcook]

hey, basically i am looking for some new supps, i have ordered whey and casein protein but am looking for a pro hormone or an "anabolic activator" and just wondered if anyone had tried leukic and what they thought. I have my doubts because it is muscletech and therefore could be a load of crap but if someone could give me some recomendations on other products too that would be great, thanks

[JakeVendetta]

Leucine is great. As for leukic dont believe everything you read. How old are you and how long have you been training? Chances are you dont need a pro hormone at this time to step you up to that next level but just harder dieting and training (with the help of a few simple supplements if the need be).

[stalion]

ive did two bottles of leukic befor i new better.

i woul rather go to the supermarket an get tons of red beef and sweetpotatoes that should sum it up

[F-111]

muscletech = no

[james69]

stuff is trash and way over priced..........tried the methyl 1ad gained a bit on it.eat big=get big. cop some creatine down the protein.

[mindstar]

Leucine is great the below is a post and a study quoted by DatBTrue on another board. I would just get some plain ole leucine and skip the leukic.
PWO - Hi-GI carbs + Leucine
20 minutes later -eat protein, carbs, even a little fat

I understand not wanting to use exogenously administered insulin. Does this mean you would lose out on insulin's contribution to GH induced anabolism?

No...you can achieve what would amount to a couple iu of Hum-R by using glucose & leucine. The two work synergistically to spike insulin.

About 3.5 grams of Leucine was sufficient to double the insulin response to 25grams of glucose. See below:

Leucine, when ingested with glucose, synergistically stimulates insulin secretion and lowers blood glucose, Dionysia Kalogeropoulou, Metabolism Clinical and Experimental 57 (2008) 1747–1752

Thereafter, they received 25 g glucose or 1 mmol/kg lean body mass leucine or 1 mmol/kg lean body mass leucine plus 25 g glucose in random order. Serum leucine, glucose, insulin, glucagon, and alpha-amino nitrogen concentrations were measured at various times during a 2.5-hour period after ingestion of the test meal. The amount of leucine provided was equivalent to that present in a high-protein meal, that is, that approximately present in a 350-g steak. After leucine ingestion, the leucine concentration increased 7-fold; and the alpha-amino nitrogen concentration increased by 16%. Ingested leucine did not affect the serum glucose concentration. When leucine was ingested with glucose, it reduced the 2.5-hour glucose area response by 50%. Leucine, when ingested alone, increased the serum insulin area response modestly. However, it increased the insulin area response to glucose by an additional 66%; that is, it almost doubled the response. Ingested leucine stimulated an increase in glucagon. Ingested glucose decreased it. When ingested together, the net effect was essentially no change in glucagon area. In summary, leucine at a dose equivalent to that present in a high protein meal, had little effect on serum glucose or insulin concentrations but did increase the glucagon concentration. When leucine was ingested with glucose, it attenuated the serum glucose response and strongly stimulated additional insulin secretion. Leucine also attenuated the decrease in glucagon expected when glucose alone is ingested. The data suggest that a rise in glucose concentration is necessary for leucine to stimulate significant insulin secretion. This in turn reduces the glucose response to ingested glucose.