[BIGSWiN19]

I've heard for a long time that glutamine and creatine compete for the same receptors, thus making one or the other useless when taken at the same time (such as post workout). I have also heard that this was just a Myth, and that glutamine and creatine don't compete for the same receptors and thats it's absolutely fine to take both in the same PWO shake. What do you guys think about this?

[Thomas_Rivera]

I've read that they don't compete for the same receptors, which would make more sense to me. I would say its fine to take them in post workout shake.

If your really concerned then just take your creatine pre workout.

[Freak]

Straight from Layne's Debunking Protein Myths Article:

Muscular Development Online Magazine - Bodybuildings Biggest Protein Myths Debunked

Myth: "Don't take your creatine with protein because protein contains glutamine and glutamine competes with creatine for the same transporter!"

The Real Deal: There's not an ounce of truth to this. Creatine and glutamine have completely different receptors. Creatine transport into skeletal muscle is regulated by the Creatine Transporter7 while glutamine transport into skeletal muscle is regulated by a system known as "System Nm." 8 The only thing these transporters have in common is that they are both sodium-dependent transporters, meaning that they use differences in sodium concentrations across the cell membrane to drive creatine into cells. Apparently somewhere along the line, somebody believed that since glutamine and creatine transporters both shared that characteristic, they must be the same transporter and the myth spread from there. Let the confusion end here: they do not share the same transporter, and taking protein/glutamine with creatine won't decrease creatine uptake into muscle.

[BIGSWiN19]

Originally Posted by thefreak350

Straight from Layne's Debunking Protein Myths Article:

Muscular Development Online Magazine - Bodybuildings Biggest Protein Myths Debunked

Myth: "Don't take your creatine with protein because protein contains glutamine and glutamine competes with creatine for the same transporter!"

The Real Deal: There's not an ounce of truth to this. Creatine and glutamine have completely different receptors. Creatine transport into skeletal muscle is regulated by the Creatine Transporter7 while glutamine transport into skeletal muscle is regulated by a system known as "System Nm." 8 The only thing these transporters have in common is that they are both sodium-dependent transporters, meaning that they use differences in sodium concentrations across the cell membrane to drive creatine into cells. Apparently somewhere along the line, somebody believed that since glutamine and creatine transporters both shared that characteristic, they must be the same transporter and the myth spread from there. Let the confusion end here: they do not share the same transporter, and taking protein/glutamine with creatine won't decrease creatine uptake into muscle.

yea, thats one of the sources I saw saying it was ok. I've always done it and never had a problem so I guess my initial opinion (its a myth) is legitified. Guess i'll keep doing the way i'm doing. Thanks dudes.

[musicmann89]

i take 10g of each pwo, seems to work fine =]