Here is something to think about. These are quotes from probably the top Nutritionist in the Nation. I enjoy and agree with him on most things.
1.
He is talking about a diet the guy that wrote Freakanomics did where he drank Fructose water almost exclusively.
Nationally known nutritionist and weight loss expert Jonny Bowden, who I was able to reach today at home, puts it succinctly.
"Fructose is the most damaging of sugars. It raises triglycerides and creates insulin resistance using a different pathway than normal," he told me.
"Sure, fructose has a low-glycemic index, but every nutritionist worth his salt has learned that its glycemic index is irrelevant to the extensive damage that it causes," Bowden, who is the iVillage.com "Weight Loss Coach" and author of Living the Low Carb Life: Choosing the Diet that's Right for You, from Atkins to the Zone.
2. Excerpt from his book "Living the Low Carb Lifestyle"
Q: Is fructose ok?
A: No. Fructose doesn't raise blood glucose levels a lot so it used to be thought the best sweetener for diabetics. Bad idea. Even though it doesn't raise blood sugar very fast it has shown to cause insulin resistance in both humans and animals. Fructose is turned into fat in the liver which raises your triglycerides.
3. Might as well throw in a study to back it all up 
Fructose, weight gain, and the insulin resistance syndrome1,2,3
Sharon S Elliott, Nancy L Keim, Judith S Stern, Karen Teff and Peter J Havel
view explores whether fructose consumption might be a contributing factor to the development of obesity and the accompanying metabolic abnormalities observed in the insulin resistance syndrome. The per capita disappearance data for fructose from the combined consumption of sucrose and high-fructose corn syrup have increased by 26%, from 64 g/d in 1970 to 81 g/d in 1997. Both plasma insulin and leptin act in the central nervous system in the long-term regulation of energy homeostasis. Because fructose does not stimulate insulin secretion from pancreatic ß cells, the consumption of foods and beverages containing fructose produces smaller postprandial insulin excursions than does consumption of glucose-containing carbohydrate. Because leptin production is regulated by insulin responses to meals, fructose consumption also reduces circulating leptin concentrations. The combined effects of lowered circulating leptin and insulin in individuals who consume diets that are high in dietary fructose could therefore increase the likelihood of weight gain and its associated metabolic sequelae. In addition, fructose, compared with glucose, is preferentially metabolized to lipid in the liver.
Fructose consumption induces insulin resistance, impaired glucose tolerance, hyperinsulinemia, hypertriacylglycerolemia, and hypertension in animal models. The data in humans are less clear. Although there are existing data on the metabolic and endocrine effects of dietary fructose that suggest that increased consumption of fructose may be detrimental in terms of body weight and adiposity and the metabolic indexes associated with the insulin resistance syndrome, much more research is needed to fully understand the metabolic effect of dietary fructose in humans.
WHEW!
