Recreate & CLA – The Perfect Fat Burning Stack!
It is well known by now that CLA, a long-chain conjugated form of linoleic acid, and actually a collective name for a group of fatty acids, is a
useful tool in combating adipocyte [fat cell] proliferation [increase in number], differentiation [development into mature, adult adipocyte cells] and hypertrophy [increase in diameter]. Well-documented research displays that certain CLA isomers, particularly the isomers contained in Tonalin CLA, regulate key lipogenic [fat-building] processes such as: a decrease in ligand-dependent fat metabolic transcription factors such as PPAR-y [peroxisome proliferated activated receptor], a transcription factor that regulates the differentiation cascade in preadipocytes by controlling key fat metabolic proteins and fat gene expression; decreasing levels of LPL [lipoprotein lipase] mRNA, a key enzyme involved in lipid [fat] transport and metabolism, and an enzyme that releases fatty-acids into the bloodstream for possible storage, and; tissue-specific decreases in glycerol-3-phosphate dehydrogenase, an enzyme that is responsible for catalyzing the glycerol-lipid pathway of phospholipid synthesis, and an enzyme that is
highly implicated in glyercol-glucose metabolism, and in insulin-resistant states.
Taken together, these fat metabolic inhibitory effects of the isomers of CLA contained within Tonalin lead to some research estimating up to a 35% reduction in total cell number, and 15-20% reduction in fat diameter–substantial markers of the anti-lipogenic effects of Tonalin CLA. Now, in addition to these stated effects of Tonalin CLA, we have the diverse matrix of Recreate: a specifically and
deliberately designed combination of extracts that substantially potentiates the effects of CLA in several ways.
For example, certain extracts in Recreate decrease both glycerol-3-phosphate dehydrogenase and PPAR-y mRNA,
the very same mechanisms that Tonalin CLA regulates! Furthermore, Recreate expands on Tonalin CLA’s anti-lipogenic [anti fat-forming] effects may providing the necessary lipolytic [fat-burning] effects – that is, Recreate contains certain ingredients that increase the oxidative metabolism of lipids and phospholipids,
ensuring that any fat that does get formed is burned – literally!
In essence, the combination of Recreate and Tonalin CLA provides the perfect potentiating stack to decimate existing adipose stores, prevent the differentiation of immature fat cells into adult fat cells, prevent fat cell division, and substantially limit the hypertrophy of existing fat cells – in other words,
the perfect fat burning stack! USPlabs Recreate @ OrbitNutrition.com CLA @ OrbitNutrition.com 
